Endocrine Abstracts

Introduction: Inflammatory markers play an important role in the development of type 2 diabetes and coronary artery disease. Monocyte chemoattractant protein-1 (MCP-1) is a member of the C-C chemokine family and a potent chemotactic factor for monocytes.The aim of our study was to investigate the effect of MCP-1 A-2518G polymorphisms on the development of diabetic coronary heart disease.Subjects and methods: 53 diabetic patients wi...

Background: Vitamin D receptor (VDR) is present on adipocytes, and many studies were carried out to investigate the association between single nucleotide polymorphisms (SNPs) in VDR gene with obesity. However, little is known about the role of VDR gene polymorphism with obesity in dialysis patients. Therefore, we aimed to investigate lipid profile and VDR gene TaqI, ApaI and FokI SNPs in overweight/obese dialysis patients.Methods: Seventy one normal weig...